Microchannel gradient centrifugation to measure single-cell density

I want to develop an instrument for precise, fast, and easy-to-use time-resolved determination of particle densities with single cell resolution. I envision that this tool can be employed in basic biology and in the medical field to study cellular processes which in many cases affect cell density. Further, accurate information about the density at single cell level will become an important tool to me and others in my research environment where we work extensively on acoustic cell separation