The object of the project is to evaluate a completely new investigation algorithm based on endodrill biopsy under local anaesthesia instead of TURB under anaesthesia. The aim is to reduce the time until definitive treatment of MIBC is initiated, since such time delay diminishes the chances of curing this potentially serious tumour where today only every other patient is cured despite radical surgery. We also predict that the new algorithm implies less patient discomfort and is more economically beneficial than TURB.