Mucopolysaccharide Type I (MPS-I) belongs to the wider group of lysosomal storage disorders. The most serious form is Hurler’s syndrome. None of the available interventions for MPS-I modify central nervous system pathology, while the proposed drug reaches CNS. The subject is not yet an approved drug, but it is now

Type 1 diabetes (T1D) is an autoimmune disease where activation of the immune system causes the cells in the pancreas that produce insulin to be destroyed. The project aims to develop a drug that can significantly reduce the risk of hypo / hyperglycaemia and sequelae; a peptide drug that will

The purpose of this project is to develop a vaccine for the treatment of MS. Treatment of MS in an animal model has been successful. The aim is to take this vaccine to market. Today’s medicines for autoimmune diseases are ineffective and not without side effects. There is, therefore, a

The project aims at initiating and implementing a Phase II trial in order to investigate whether an already approved diagnostic drug can be used for the detection of kidney cancer. Diagnostics could in a conclusive way contribute to a more detailed analysis of the metastasis in these patients than is

Sepsis is a general inflammatory reaction caused by an infection, often bacterial. The most common method of finding out if the reaction is caused by bacteria in the blood; and then identifying them is growing the bacteria from a blood sample, which can take one to several days. This is

Pancreatic cancer is one of the most serious forms of cancer. The difficulty is to identify pancreatic cancer “early”. There are no biomarkers in either blood or tissue to provide diagnosis, prognostic / predictive help and support in selecting therapy. Research has now found a pancreatic cancer-specific marker (Histone 1.3;

Glioblastoma is the most common primary brain tumour in humans. It is a diagnosis with a very bleak outcome. The goal is to analyse whether glioblastoma expresses C1-IA and CRP (proteins) that inhibit immune response by inactivating the complement system, and to test treatment in various animal models for glioblastoma.

The development of cardiovascular care in the western world is being driven towards less invasive methods, where so-called catheterization replaces open heart surgery. Many patients with heart disease must undergo open heart surgery treatment, which is a major operation that is not without its risks. In the past 10 years

Pulmonary hypertension is a fatal condition in many cases. A prerequisite for better treatment is an increased understanding of pathophysiology and lung microanatomy. Until now, no satisfactory 3D imaging methods have been available. Further, the goal is to create automated measurement of the thickening of lung vessels. The methods used

The purpose of the study is to be able to, using an early diagnosis of hypomineralized molars provide the best preventative treatment to minimize the risk of caries or later acute symptoms as well as more complicated treatments. Through this study, dentist and dental hygienists can work more towards preventing