The incidence of bladder cancer is on the increase in Sweden. The purpose of the project is to apply molecular classification with RNA sequencing technology in clinical practice to bladder cancer cases. By analysing the expression of every gene in the tumour cells, bladder cancer can be classified into subtypes,

Ovarian cancer is the main cause of death from gynaecological malignancies in the western world. The aim of the study is to develop a non-invasive diagnostic test for pre-symptomatic diagnosis of ovarian cancer. Early detection would have a profound effect on survival, which enables curative treatment for these patients. Achieving

Mucopolysaccharide Type I (MPS-I) belongs to the wider group of lysosomal storage disorders. The most serious form is Hurler’s syndrome. None of the available interventions for MPS-I modify central nervous system pathology, while the proposed drug reaches CNS. The subject is not yet an approved drug, but it is now

Type 1 diabetes (T1D) is an autoimmune disease where activation of the immune system causes the cells in the pancreas that produce insulin to be destroyed. The project aims to develop a drug that can significantly reduce the risk of hypo / hyperglycaemia and sequelae; a peptide drug that will

The purpose of this project is to develop a vaccine for the treatment of MS. Treatment of MS in an animal model has been successful. The aim is to take this vaccine to market. Today’s medicines for autoimmune diseases are ineffective and not without side effects. There is, therefore, a

The project aims at initiating and implementing a Phase II trial in order to investigate whether an already approved diagnostic drug can be used for the detection of kidney cancer. Diagnostics could in a conclusive way contribute to a more detailed analysis of the metastasis in these patients than is

Sepsis is a general inflammatory reaction caused by an infection, often bacterial. The most common method of finding out if the reaction is caused by bacteria in the blood; and then identifying them is growing the bacteria from a blood sample, which can take one to several days. This is

People with Type 1 diabetes lack the hormone insulin. Insulin is vital to the body’s cells for the supply of energy and the progression of metabolic processes. Insulin must therefore be administered daily through multiple injections or an insulin pump. Self-regulating pumps, so-called artificial pancreas, are not available yet. In

The elderly and the chronically ill with personal alarms with panic buttons are exposed daily to high risk in their own home environment; no one hears when they are in urgent need of help and that’s why assistance is not available. The vital communication through personal alarms with panic buttons

The development of cardiovascular care in the western world is being driven towards less invasive methods, where so-called catheterization replaces open heart surgery. Many patients with heart disease must undergo open heart surgery treatment, which is a major operation that is not without its risks. In the past 10 years