Diamond-Blackfan anaemia (DBA) is an inherited chronic disease in which patients suffer from severe anaemia. There is at present no treatment that specifically corrects the cause of the anaemia. Instead, patients are treated from infancy with blood transfusions or corticosteroids, which over time, leads to serious side effects and premature

The aim is to develop a new instrument and a method for taking samples of all types of cancer suspected abnormalities detected by endoscope (a flexible tube with camera equipment). The most commonly studied systems and survey areas are the stomach, the intestines and the respiratory system. An instrument that

The goal of this project is to develop an initial verification of a new method for the treatment of multiple sclerosis (MS), an autoimmune disease. About 900-1000 people are diagnosed with MS every year in Sweden. Current treatments are ineffective and often not specific for MS, and can lead to

The lung disease COPD, according to WHO, is the fourth most common cause of death worldwide, and its prevalence is increasing. Of the more than 200 million people suffering from COPD, three million die annually. The diagnostic method that is most specific for emphysema is computed tomography (CT scan) –

Breast cancer is according to WHO the second most common cancer in the world. Treatment is usually surgery in combination with chemotherapy and / or radiation and for the majority of patients followed by a 5-year anti-oestrogen therapy to prevent relapse. The project intends to develop a unique p-rod-like implant

The project received a grant from the Sten K. Johnsson Foundation in 2015. Since then, the following has happened: 1) a needle prototype has been developed with JOIN in Lund. 2) A study of the needle at the Centre of Bacteriology at Lund University has shown that: a) the needle

In order to achieve the vision of personalised cancer treatment, clinical pathology must develop better tools to be able to “predict in the tissue”, i.e., identify biological properties, known as biomarkers, in individual tumours, which are of significance to disease progression (prognosis) and the effect of different treatments (prediction). The

Several of the most deadly bacteria in the world alternate between causing symptomatic infections and acting as asymptomatic carriers, where they do not harm their host. One of these is the group A streptococci (GAS). GAS has a control system which switches off or on the virulence factors, that is,

Pancreatic cancer is one of the most serious forms of cancer. The difficulty is to identify pancreatic cancer “early”. There are no biomarkers in either blood or tissue to provide diagnosis, prognostic / predictive help and support in selecting therapy. Research has now found a pancreatic cancer-specific marker (Histone 1.3;

Glioblastoma is the most common primary brain tumour in humans. It is a diagnosis with a very bleak outcome. The goal is to analyse whether glioblastoma expresses C1-IA and CRP (proteins) that inhibit immune response by inactivating the complement system, and to test treatment in various animal models for glioblastoma.