2D-to-3D biofidelic computational models to better assess fracture risk in osteoporotic men

The aim of the current proposal is to evaluate the accuracy of 3D patient-specific computational models based on 2D-to-3D reconstruction and a biofidelic estimation of fall to estimate fracture risk in a clinical cohort including 1000 men living in Skåne. The predicted outcome is compared to the current clinical standard. The hypothesis is that including these models into the fracture risk prediction algorithm can significantly improve the prediction accuracy.