Sorting based on secretion using advanced microfluidics and bioresponsive hydrogels

We aim to contribute to a better understanding of what governs an individual cell’s secretion of different substances and the role played by external chemical stimuli. It will lay the basis for utilization in several areas. Diabetes is based on a disorder of the secretion of insulin by beta cells and glycogen by alpha cells as a function of glucose concentration in the surrounding area. Infectious diseases are another area where chemical communication between pathogens is important for the formation of biofilms which play a major role in the onset of an infection. Bacterial secretion of enzymes is important for the occurence of resistance to antibiotics.