C4BP-IgM fusion protein as a novel therapeutic approach to cure Neisseria gonorrhoeae infection

We aim to present a unique therapeutic approach to curing gonococcal infection. The C4BP-IgM fusion protein is an innovative drug because it takes advantage of evasion mechanisms developed by bacteria to escape immune system recognition. C4BP binds to bacterial surface, while the constant portion of IgM promotes serum-mediated killing of pathogens. We also propose to show that this protein is specific, effective and non-toxic for the patient.